For NY Giants fans, they’re not going to stop talking about Week 1 of the 2022 season until the big day arrives. As was revealed on Thursday, New York will take on the Tennessee Titans on Sept. 11 in Nashville to open the season. After going 4-13 last year, the pressure will be on the G-Men to bounce back in a big way this fall.
While it won’t be easy, there’s plenty of reason to believe that head coach Brian Daboll can get this group back on track. In this article, we break down every contest and offer up our predictions. Will the Giants end up sneaking into the playoffs?
NY Giants game-by-game prediction for 2022 schedule
Week 1: NY Giants at Tennessee Titans
This won’t be an easy showdown for the Giants, as Ryan Tannehill is a savvy veteran quarterback and Derrick Henry is an absolute unit running the ball. The opening line is out and Tennessee, to no one’s surprise, is favored to come away with a road win. We think the Giants will make things interesting, but we’re going with Tennessee to record a victory.
Prediction: Titans 28-Giants 20
Week 2: NY Giants vs. Carolina Panthers
Come Sept. 18, the Giants will make their 2022 MetLife Stadium debut and host the Carolina Panthers. This will mark a return to the area for Sam Darnold, who spent three awful years with the New York Jets. Darnold might be fired up to try and light up his former stomping grounds, but we think Daniel Jones will get the better of him.
Prediction: Giants 24-Panthers 17
Week 3: NY Giants vs. Dallas Cowboys on MNF
Get your popcorn ready for some Monday Night Football action. That’s right, in Week 3, Dallas and New York will take centerstage, with the Giants hosting the Cowboys for this one. The pressure will be on Jones and Saquon Barkley in primetime. Dallas will hope to record a head-turning win, but an upset might be in the air that night. Look for the Giants to come out on top in a high-scoring affair.
Prediction: Giants 31-Cowboys 28
Week 4: NY Giants vs. Chicago Bears
In another home game, the Giants will have a fantastic opportunity to record another win, this time against the Bears. Justin Fields is still a young quarterback and the former first-round pick sure had his struggles last year. With the Giants holding an impressive pass-rush thanks to the addition of Kayvon Thibodeaux, the Giants could make Fields’ life difficult from start to finish in this matchup. Advantage New York.
Prediction: Giants 27-Bears 17

Week 5: NY Giants at Packers in London
Tottenham Hotspur Stadium is going to be packed for the Oct. 9 matchup between the Giants and Green Bay Packers. Aaron Rodgers will play overseas in the United Kingdom for the first time in his career. And it goes without saying, but no Davante Adams will have a negative impact on him. However, Green Bay will still be able to move the ball around thanks to Rodgers’ cannon. Green Bay takes it.
Prediction: Packers 28-Giants 14
Week 6: NY Giants vs. Baltimore Ravens
Things unfortunately won’t get easier for the Giants the following week, as Baltimore and Lamar Jackson will make their way to town. Jackson is one of the most dynamic quarterbacks in the game, hurting teams with his arm and wheels. New York could make this a close one, but Jackson and Co. will prove to be too much.
Prediction: Ravens 24-Giants 17
Week 7: NY Giants at Jacksonville Jaguars
Everything looked so promising for the Jaguars last season, but then everything went up in flames. Urban Meyer is out as head coach and former No. 1 pick Trevor Lawrence sure looked tough at times. People are excited about the future for the Jags, but things are going to take some time. This will be big for NY come Week 7, as they should be able to capture win No. 4 on the year.
Prediction: Giants 21-Jaguars 14
Week 8: NY Giants at Seattle Seahawks
The Russell Wilson era for the Seattle Seahawks is over, as he’s now ready to make plays with the Denver Broncos. Drew Lock is lined up to be the starter for Seattle, which its fans aren’t too excited about. Despite that, running backs Rashaad Penny and Kenneth Walker (just drafted) have what it takes to be quite the combo. Lock will be a game manager and do enough to power his side to a win against NY.
Prediction: Seahawks 21-Giants 20
Week 9: NY Giants have a BYE This week
Enjoy this Sunday off, Giants fans. New York has a BYE for Week 9 and will be out of action this weekend.

Week 10: NY Giants vs. Houston Texans
This will be a no-excuse game for the Giants and Jones. The Texans were one of the worst teams in the NFL last season and that figures to be the case once again in 2022. The majority of NFL Mock Drafts for 2023 already have them taking home the No. 1 pick. If ever there was a game for Jones to put up huge numbers, this would be it.
Prediction: Giants 35-Texans 21
Week 11: NY Giants vs. Detroit Lions
This is another winnable contest for the Giants, as Detroit leaves much to be desired on both sides of the ball. Jared Goff will look to have a big game in this one, as will stud receiver Amon-ra St. Brown. The addition of Jameson Williams could be big for Detroit too. Again, this is a winnable game for the Giants, but we think they slip up.
Prediction: Lions 21-Giants 14
Week 12: NY Giants at Dallas Cowboys (Thanksgiving Game)
Get ready for some turkey day action, as the G-Men will be headed to AT&T Stadium to meet the Dallas Cowboys. As inconsistent as Dallas has been offensively, this will be a matchup where Dak Prescott and the rest of the offense really find a rhythm. It could prove to be a long day at the office for Jones and Co.
Prediction: Cowboys 28-Giants 14
Week 13: NY Giants vs. Washington Commanders
Come Dec. 4, New York will host Washington in what should be a back-and-forth meeting. For Washington, everyone will be waiting to see if stud running back Antonio Gibson can stay healthy. He’s battled injuries early on in his career. Regardless of that, Barkley will have the pep in his step to out-perform him. Let’s go with 135 total yards and two scores for Barkley in a win.
Prediction: Giants 28-Commanders 21

Week 14: NY Giants vs. Philadelphia Eagles
There will be some extra drama for this Dec. 11 tilt, especially if the Eagles go out and sign cornerback James Bradberry. No one in East Rutherford wants to see this go down. On offense, Philadelphia got stronger thanks to the addition of standout wideout A.J. Brown. NY will keep this one tight, but look for Philly to leave New Jersey with a win.
Prediction: Eagles 27-Giants 21
Week 15: NY Giants at Washington Commanders
A trip to FedEx Field is on the schedule for Week 15. We discussed the health concerns for Gibson above, but Washington also now features quarterback Carson Wentz. Wentz is no stranger to the Giants, as he played them multiple times while with the Eagles. Wentz has loads of people doubting him, but when he’s on, he’s really on. Will Wentz get the job done at home against New York?
Prediction: Commanders 30-Giants 23
Week 16: NY Giants at Minnesota on Christmas Eve
Another holiday contest for the Giants? That’s indeed the case come Christmas Eve, as Kirk Cousins, Dalvin Cook and Justin Jefferson will be ready to put on a show vs. the New York defense. Minnesota hasn’t delivered in recent seasons, but they do feature a scary offense when firing on all cylinders. We think that will be the case on X-Mas Eve.
Prediction: Vikings 34-Giants 21
Week 17: NY Giants vs. Indianapolis Colts
In the final meeting at MetLife Stadium for the year, the new-look Colts will be in town. Matt Ryan will be donning and Indy jersey, which is weird to think about. It will also be a bit of a homecoming for south New Jersey product Jonathan Taylor. This will be another close game, but we like the Colts to land the final punch with a game-winning field goal late.
Prediction: Colts 24-Giants 21
Week 18: NY Giants at Philadelphia Eagles
To close the campaign out, the Giants will head over the Lincoln Financial Field for a showdown with Jalen Hurts and Co. This could be a game which decides whether or not the Eagles will make the playoffs, so they’ll be playing with some extra urgency. This will lead to Philly taking out any anger they have on the Giants in a lopsided win.
Prediction: Eagles 28-Giants 13
NY Giants final record prediction for 2022
After going 4-13 last year, plenty of fans were beyond angry with the Giants. Now, things are looking bright with general manager Joe Schoen and head coach Brian Daboll working together. While we don’t think the Giants will win the division or make the playoffs, expect them to take a step up from the four-win campaign in ’21. We predict the Giants to go 7-10 in 2022.

