ESPN NFL Picks: Week 5

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Sep 19, 2013; Philadelphia, PA, USA; Kansas City Chiefs running back Jamaal Charles (25) carries the ball during the second quarter against the Philadelphia Eagles at Lincoln Financial Field. The Chiefs defeated the Eagles 26-16. Mandatory Credit: Howard Smith-USA TODAY Sports

Kansas City @ Tennessee
Chiefs are 4-0. The Titans’ offense is ranked 29th and the Chiefs’ defense is ranked third. This is a big mismatch in the Chiefs’ favor. Chiefs’ starting RB Jamaal Charles has been in limited practices this week due to blisters on his feet but I can’t imagine that blisters are going to keep him out of the game. Chiefs win.