Giants Game Sunday: Giants vs Los Angeles Rams Odds and Prediction for Week 6 NFL Game

The undermanned Giants aim to pull of an upset of the NFC West’s Los Angeles Rams in Week 6 of the 2021 NFL Season 

The Giants (1-4), led by head coach Joe Judge, wide receiver Kadarius Toney, and tight end Evan Engram, host the Los Angeles Rams (4-1), led by quarterback Matthew Stafford, wide receiver Cooper Kupp, and defensive tackle Aaron Donald, in an NFL Week 6 game at MetLife Stadium in East Rutherford, New Jersey, on Sunday, October 17, 2021 (10/17/2021) at 1 p.m. on FOX.

New York aims to bounce back from a disastrous loss to the Dallas Cowboys, that saw quarterback Daniel Jones (concussion), running back Saquon Barkley (ankle), and wide receiver Kenny Golladay (knee) knocked out with significant injuries.

Here’s everything you need to know about NY Giants vs. Los Angeles Rams in Week 6 of the NFL Season:

Giants vs Rams Odds Week 6

According to WynnBET, the NY Giants open as 10.5 point underdogs to the Rams, and the over/under is 47.5. The Giants are +450 on the moneyline, meaning that a $100 bet on the Giants would pay $450 if New York pulls off the upset.

Giants vs. Rams Prediction NFL Week 6

The Rams arrive as arguably the most complete team in the most competitive division in football, with quarterback Matthew Stafford operating on the fringes of the NFL MVP conversation after five weeks. Already with quality wins over the Tampa Bay Buccaneers and Seahawks, the Rams have legitimate Super Bowl aspirations in the NFC. Meanwhile, the Giants could be without three of their most important players on offense and if the season ended today would be picking in the top-10 selections in the NFL Draft. Given that the Rams had extra time to prepare, after playing last Thursday night, there’s little reason to believe this game ends up particularly close.

Prediction: Rams 37, Giants 16

Make your pick on WynnBET.com